Conventional transarterial chemoembolization versus drug-eluting bead transarterial chemoembolization for the treatment of hepatocellular carcinoma

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Conventional versus doxorubicin-eluting bead transarterial chemoembolization for hepatocellular carcinoma.

PURPOSE To compare short- and long-term clinical outcomes after conventional transarterial chemoembolization and drug-eluting bead (DEB) transarterial chemoembolization in hepatocellular carcinoma (HCC). MATERIALS AND METHODS Patients with unresectable HCC unsuitable for ablative therapies were randomly assigned to undergo conventional or DEB chemoembolization. The primary endpoints of the st...

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Transarterial chemoembolization with drug-eluting beads versus conventional transarterial chemoembolization in locally advanced hepatocellular carcinoma

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Hemorrhage Following Drug-Eluting Bead Transarterial Chemoembolization of Hepatocellular Carcinoma

We report the case of a 78-year-old woman with hepatocellular carcinoma who underwent drug-eluting bead transarterial chemoembolization (DEB-TACE). On the first routine follow-up CT six-weeks post procedure, the patient was found to have residual enhancing tumor and active intra-tumoral hemorrhage (Fig 1A). Follow-up laboratory values demonstrated a decrease in hemoglobin. Subsequent catheter a...

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Conventional vs drug-eluting beads transarterial chemoembolization for hepatocellular carcinoma

Transarterial chemoembolization (TACE) is the current standard of therapy for patients with intermediate-stage hepatocellular carcinoma (HCC) according to the Barcelona Clinic Liver Cancer classification. The concept of conventional TACE (cTACE) is the selective obstruction of tumor-feeding artery by injection of chemotherapeutic agents, leading to ischemic necrosis of the target tumor via cyto...

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Transarterial chemoembolization with drug-eluting beads in hepatocellular carcinoma

Transarterial chemoembolization (TACE) is a widely used standard treatment for patients with hepatocellular carcinoma (HCC) who are not suitable candidates for curative treatments. The rationale for TACE is that intra-arterial chemotherapy using lipiodol and chemotherapeutic agents, followed by selective vascular embolization, results in a strong cytotoxic effect as well as ischemia (convention...

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ژورنال

عنوان ژورنال: BMC Cancer

سال: 2015

ISSN: 1471-2407

DOI: 10.1186/s12885-015-1480-x